Review of Research Paper on Insulin :: Biology Diabetes

Missing GraphsBACKGROUNDLets go subscribe to the 1920s, when diabetes was discovered and the study of glucosebegan. There was a scientist named Minkowsky, and he wondered what caused diabetes. So, hedid something half-baked He took a urine exemplification from a normal unhurried and a sample from adiabetic patient, and tasted them He observed that the sample from the diabetic patient wassweet, so he concluded that diabetes had something to do with utmost glucose levels (lots ofsugar in the blood).In the same decade, two scientists named Benting and Best performed other essay to see which chemic completelyy made pancreas would do the best play in lowering glucoselevels. This led to the discovery of insulin.Moving on to the 1940s, scientists were comical about what exactly insulin had to dowith glucose. Basically, insulin increases the amount of glucose that gets transported to theplasma membrane of all cell in your body, so the breakdown of glucose will be faster.Now, the fo refront was quantity vs. quality did insulin actually make the glucosetransporters work better, or did insulin just increase the number of glucose transporterswithin each cell? This is what this paper answers. PROCEDURESWhen looking for at the systems in this paper, it is easy to get lost and confused amidst allthe scientific terms and complicated language. However, when broken down into simpler terms,the methods used in the experiment in the paper become much clearer and create a basis forunderstanding for the remainder of the paper.Following is a short and apprehensible explanation of the methods used in the paper and also an explanation of the experiment that was performed to reach to conclusions in the paper. * The first method mentioned in the paper is the collagenase method. This method refers to the collagen that holds the fat cells that were extracted from the rats together. * This method is simply the breaking down of the collagen between the cells in order to separate and isolate them. * Another method used in the paper is refereed to when talking about homogenizing the cells. * This method refers to mixing up and press of the fat cells to make into an evenly distributed soup like substance that do-nothing then be used in the experiment. When the homogenized soup is prepared, it is them site into a centrifuge tube and centrifuged.